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The U.S. Food and Drug Administration reviewed Contrave on December 7, and approved the drug 13-7, stating the advantage of the drug outweighs the potential risk of a possible surge in blood pressure. Using two separate drugs to shed weight can be very effective you will find combinations while watching FDA now awaiting approval. When dealing with weight-loss and the individuals who go through it you need to err on the side of caution and allow FDA do its job and demand some study be done so your public understands the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies come in business to generate money and that they would say almost anything to keep people on his or her medications. Researchers discovered that participants using this drug to get a year, lost weight within one month and have kept the extra weight off during the entire 56 weeks of the study. Contrave is really a combination of the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs which might be made up of more than one active ingredient, which might make them more efficient and safer. Combo-pilling will be the newest fad or also the newest into the future under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular could be the fact that as of right now there are no long term prescription diet pills that have been authorized by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be licensed by the FDA. Seizures certainly are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug could also raise blood pressure levels and heart rate, and mustn't be used in people who have a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure and pulse rate and must stop used in patients with uncontrolled high blood pressure levels, as well as by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients which has a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients to the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking. An independent report published by Gant Daily in April also stated that naltrexone also works best for kleptomaniacs and gambling addicts, also. Citing research through the University of Minnesota School of Medicine, Gant Daily reported the drug conditions kleptomaniacs and chronic gamblers just like with alcohol and opioid addicts'by blocking the results of endorphins, that the brain releases when experiencing craving or compulsions.